Omega-3 Supplementation and Its Effects on Osteoarthritis
Osteoarthritis (OA) is a degenerative joint disease characterized by the destruction of the articular cartilage, resulting in a pro-inflammatory response. The progression of OA is multifactorial and is influenced by the underlying cause of inflamm...
Shawl M, Geetha T, Burnett D et al. — Nutrients
Omega-3-fatty acids: Do they prevent cardiovascular disease?
Despite cardiovascular disease (CVD) reductions with high-intensity statins, there remains residual risk among patients with metabolic disorders. Alongside low-density lipoproteins (LDL-C), elevated triglycerides (TG) are associated with incident ...
Mason RP, Sherratt SCR, Eckel RH — Best practice & research. Clinical endocrinology & metabolism
Efficacy of omega-3 PUFAs in depression: A meta-analysis
We conducted this meta-analysis of double-blind randomized placebo-controlled trials to estimate the efficacy of omega-3 polyunsaturated fatty acids (PUFAs), especially docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), in the improvement...
Liao Y, Xie B, Zhang H et al. — Translational psychiatry
Omega-3 fatty acids and inflammatory processes: from molecules to man
Inappropriate, excessive or uncontrolled inflammation contributes to a range of human diseases. Inflammation involves a multitude of cell types, chemical mediators and interactions. The present article will describe nutritional and metabolic aspec...
Calder PC — Biochemical Society transactions
Impact of Omega-3 Fatty Acids on the Gut Microbiota
Long-term dietary habits play a crucial role in creating a host-specific gut microbiota community in humans. Despite the many publications about the effects of carbohydrates (prebiotic fibers), the impact of dietary fats, such as omega-3 polyunsat...
Costantini L, Molinari R, Farinon B et al. — International journal of molecular sciences
Marine omega-3 fatty acids and inflammatory processes: Effects, mechanisms and clinical relevance
Inflammation is a condition which contributes to a range of human diseases. It involves a multitude of cell types, chemical mediators, and interactions. Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are omega-3 (n-3) fatty acids found...
Calder PC — Biochimica et biophysica acta
Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?
Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are n-3 fatty acids found in oily fish and fish oil supplements. These fatty acids are able to inhibit partly a number of aspects of inflammation including leucocyte chemotaxis, adhesion m...
Calder PC — British journal of clinical pharmacology
Omega-3 fatty acids and inflammatory processes
Long chain fatty acids influence inflammation through a variety of mechanisms; many of these are mediated by, or at least associated with, changes in fatty acid composition of cell membranes. Changes in these compositions can modify membrane fluid...
Calder PC — Nutrients
Omega-3 fatty acids EPA and DHA: health benefits throughout life
Omega-3 [(n-3)] fatty acids have been linked to healthy aging throughout life. Recently, fish-derived omega-3 fatty acids EPA and DHA have been associated with fetal development, cardiovascular function, and Alzheimer's disease. However, because o...
Swanson D, Block R, Mousa SA — Advances in nutrition (Bethesda, Md.)
Omega-3 fatty acids in inflammation and autoimmune diseases
Among the fatty acids, it is the omega-3 polyunsaturated fatty acids (PUFA) which possess the most potent immunomodulatory activities, and among the omega-3 PUFA, those from fish oil-eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)--are ...
Simopoulos AP — Journal of the American College of Nutrition